MOLECULAR DYNAMICS PHOSPHORIMAGING SYSTEM

分子动力学磷光成像系统

• 批准号: 3521910
• 负责人: George N. ABRAHAM
• 金额: $ 19万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-04-27 至 1994-04-26
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3521910
• 关键词: biomedical equipment purchase; biomedical equipment resource; computer data analysis; image processing; molecular biology; radiation detector

The proposal represents a coordinated effort to fill the needs of approximately 150 investigators who undertake research in molecular biology or protein chemistry and require sensitive, rapid quantitative analysis of techniques which rely for detection of a radioactive signal. The request is supported by a primary user group of sixty investigators who would use these instruments. Appropriate institutional support has been committed for technical consultants, placement of the instruments at two sites which would be convenient for all faculty who would use the instruments, provision of ancillary funds for purchase of peripheral data processing work-stations and software, and for networking the instruments to the peripheral computers for off-site data storage and manipulation. Plans for upkeep and maintenance of the instruments, scheduling of their judicious use, and access for junior unfunded investigators, have been provided. The instruments will be considered as part of the University's molecular resources core and will be administered by the advisory committee headed by Dr. George Abraham, Associate Dean for Research and Professor of Medicine, Dr. Barbara Iglewski, Professor and Chair of Microbiology and Immunology, Dr. Martin Gorovksy, Professor and Chair of Biology, Dr. Fred Sherman, Professor and Chair of Biochemistry, and Dr. Terry Platt, Professor of Biochemistry. The addition of these instruments to the Molecular Biology facility at the University and Medical School will be of great benefit to its investigators, will markedly diminish the need for and waste from radioactive chemicals and autoradiographic techniques, and will provide all scientists with a system for data analysis of excellent precision which has hitherto not been present in any form at this major research center.

该提案代表了为满足以下需求而做出的协调努力 大约 150 名研究人员从事分子研究 生物学或蛋白质化学，需要灵敏、快速的定量 分析依赖于放射性信号检测的技术。 该请求得到了由 60 名调查员组成的主要用户组的支持 谁会使用这些工具。适当的机构支持 致力于技术顾问，将仪器放置在 两个站点对于所有使用该系统的教职人员来说都很方便 仪器、提供辅助资金购买外围数据 处理工作站和软件，以及网络 仪器到外围计算机以进行异地数据存储 和操纵。仪器的维护和保养计划， 明智地安排其使用，并为没有资金的初级人员提供访问机会 调查人员已提供。这些文书将被视为 大学分子资源核心的一部分并将被管理 由乔治·亚伯拉罕博士领导的咨询委员会， 研究副院长兼医学教授 Barbara 博士 Iglewski，微生物学和免疫学教授兼主席，博士 Martin Gorovksy，生物学教授兼主席，Fred Sherman 博士， 生物化学系教授兼系主任，Terry Platt 博士，教授 生物化学。将这些仪器添加到分子生物学中 大学和医学院的设施将为其带来巨大的好处 研究人员将显着减少对 放射性化学品和放射自显影技术，并将提供 所有科学家都拥有高精度数据分析系统 迄今为止尚未以任何形式出现在这个主要研究中心。