Cognitive decline in type 2 diabetes: Investigating the contribution of neurodegeneration and cerebrovascular disease

2 型糖尿病的认知能力下降：研究神经退行性变和脑血管疾病的影响

• 批准号: nhmrc : 634504
• 负责人: A/Pr Wendy Davis
• 金额: $ 40.58万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cognitive-decline-type-cerebrovascular-disease/82008
• 关键词: Cognitive; decline; type; diabetes; Investigating

Dementia occurs more commonly than expected in diabetes but the reasons are unknown. There could be a build up of deposits of the toxic protein in the brain that causes Alzheimer's disease. A new technique, using Positron Emmission Tomography (PET scans), will be used to answer this question in combination with MRI scans and serial cognitive testing in patients considered to be at-risk for dementia. The study will help direct research efforts aimed at dementia prevention and treatment.

痴呆症在糖尿病中比预期的更常见，但原因尚不清楚。可能是大脑中有毒蛋白质的沉积导致了阿尔茨海默病。一种新的技术，使用正电子发射断层扫描（PET扫描），将被用来回答这个问题，结合MRI扫描和一系列认知测试的患者被认为是在痴呆症的风险。这项研究将有助于指导旨在预防和治疗痴呆症的研究工作。