Radio-Frequency Atomic Magnetometers for Medical Applications

用于医疗应用的射频原子磁力计

• 批准号: EP/P034152/1
• 负责人: Ferruccio Renzoni
• 金额: $ 16.93万
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FP034152%2F1
• 关键词: Radio; Frequency; Atomic; Magnetometers; Medical

The project aims to combine a novel approach to measurement (mapping of low-conductivity samples) with the implementation of a novel type of sensor which results in a Magnetic Induction Tomography system for medical applications. This relies on a recent (2014) breakthrough by the UCL team, the demonstration of electromagnetic imaging with atomic magnetometers, and the subsequent (2016) proposal for its application in the diagnosis of atrial fibrillation. So far, only passive magnetic field mapping of the heart with a non-invasive method has been possible, whereas other conductivity mapping techniques require surgery. The developed technique for magnetic heart imaging through magnetic induction tomography would provide an unique alternative to invasive mapping of arrhythmia. The proposed research includes the following activities: (a) The assembly of an rf-atomic magnetometer portable system, and the evaluation of its performance in unshielded environment. This is required to assess the suitability for the operation in a clinical environment.(b) Demonstration of magnetic induction at 1 MHz, and determination of the sensitivity of the apparatus for this type of measurements. This will be done by inducing eddy currents in a sample object and detecting the resulting magnetic field. The aim is to be able to detect a disk of 1 mm diameter and 1 mm thickness, and with conductivity corresponding to biological samples. This will pave the way for the use of the magnetometer in imaging for medical applications which will be the object of the research beyond the feasibility study associated with the present proposal. (c) Development of the detection system components that will allow integration with imaging system.

该项目旨在将联合收割机一种新的测量方法（低电导率样品的映射）与一种新型传感器的实施相结合，从而形成用于医疗应用的磁感应断层扫描系统。这依赖于UCL团队最近（2014年）的突破，原子磁力计电磁成像的演示，以及随后（2016年）将其应用于房颤诊断的提案。到目前为止，只有被动磁场标测心脏的非侵入性方法是可能的，而其他电导率标测技术需要手术。通过磁感应断层扫描的磁心脏成像技术的发展将提供一个独特的替代侵入性标测心律失常。拟议的研究包括以下活动：（a）组装射频原子磁力仪便携式系统，并评价其在无屏蔽环境中的性能。这是评估临床环境中操作适用性所必需的。(b)演示1 MHz下的磁感应强度，并确定仪器在此类测量中的灵敏度。这将通过在样品对象中感应涡电流并检测产生的磁场来完成。目标是能够检测直径为1 mm、厚度为1 mm的圆盘，并具有与生物样品相对应的电导率。这将为磁力计用于医疗成像铺平道路，这将是与本提案相关的可行性研究之外的研究对象。(c)开发可与成像系统集成的检测系统组件。