X-RAY MICROANALYSIS AND IMAGE PROCESSING SYSTEM

由一组视觉研究人员提出申请，以获得对 一台最先进的能量色散X射线的获取 显微分析和图像处理系统。该系统将被用来 更新已在共享基础上使用的扫描电子显微镜 眼科。需要这种新的工具来实现 小组成员对变化进行定量微量分析 眼组织中的细胞外和细胞内电解质(例如， 在保存角膜组织以供移植期间，在病理学上 条件和随后的各种药物治疗)。图像处理 需要能力来实现精确的量化(例如， 不同条件下角膜新生血管的比率，角膜新生血管的比率 不同药物对正常和糖尿病动物角膜创面愈合的影响 药物和化合物，以及再生眼细胞的大小和形状)。 这种新仪器的使用将促进研究 努力使人们更好地了解 威胁视力的病理性疾病。

Application is made by a group of vision researchers to obtain support for the acquisition of a state-of-the-art energy dispersive x-ray microanalytical and image processing system. The system would be used to update a scanning electron microscope already used on a shared basis in the Department of Ophthalmology. This new instrumentation is needed to enable members of the group to do quantitative microanalysis of alterations in extracellular and intracellular electrolytes in ocular tissues (e.g., during preservation of corneal tissue for transplantation, in pathological conditions and following treatment with various drugs). Image processing capabilities are needed to allow for precise quantitation (e.g., of the rate of corneal neovascularization under various conditions, the rate of corneal wound healing in normal and diabetic animals treated with various drugs and compounds, and the size and shape of regenerated ocular cells). The availability of this new instrumentation will facilitate research efforts leading to a better understanding of the mechanisms involved in sight-threatening pathological conditions.