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Combating the global medical challenge caused by Gram-negative 'superbugs': from redeveloping the polymyxins to discovering novel antibiotics

Combating the global medical challenge caused by Gram-negative 'superbugs': from redeveloping the polymyxins to discovering novel antibiotics
应对革兰氏阴性“超级细菌”造成的全球医学挑战:从重新开发多粘菌素到发现新型抗生素
批准号:
nhmrc : 1002788
负责人:
Prof Jian Li
金额:
$25.01万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Research Fellowships
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2014-12-31

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中文摘要
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英文摘要
Bacterial �superbugs� are becoming a major global medical challenge. Polymyxins are the last-line antibiotics against Gram-negative �superbugs� but with little pharmacological information available. I am an antimicrobial pharmacologist specialised in re-developing polymyxins, and discovering novel antibiotics against these very troublesome bacteria. My research targets the _Bad Bugs, No Drugs� disaster highlighted by the Infectious Diseases Society of America and the World Health Organization.
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A systems approach to combat the significant antibiotic resistance challenge: Novel therapeutic strategies, mechanistic discoveries, and drug development
  • 批准号:
    nhmrc : GNT1157909
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $78.54万
  • 财政年份:
    2019
  • 负责人:
    Prof Jian Li
  • 依托单位:
Targeting the unmet global medical need caused by Gram-negative 'superbugs': from antibiotic discovery to novel therapeutic strategies
  • 批准号:
    nhmrc : 1063069
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $46.49万
  • 财政年份:
    2014
  • 负责人:
    Prof Jian Li
  • 依托单位:
Bad Bugs Need Drugs: combating antibiotic resistance caused by bacterial ‘superbugs’
  • 批准号:
    nhmrc : GNT1063069
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $66.45万
  • 财政年份:
    2014
  • 负责人:
    Prof Jian Li
  • 依托单位:
Targeting an impending global disaster: the mismatch between increasingly drug-resistant superbugs and development of new antibiotics
  • 批准号:
    FT100100002
  • 项目类别:
    ARC Future Fellowships
  • 资助金额:
    $0.0万
  • 财政年份:
    2010
  • 负责人:
    Prof Jian Li
  • 依托单位:
国内基金
海外基金
Identification and quantification of primary phytoplankton functional types in the global oceans from hyperspectral ocean color remote sensing
  • 批准号:
    --
  • 项目类别:
    --
  • 资助金额:
    160万元
  • 批准年份:
    2022
  • 负责人:
    李忠平
  • 依托单位:
中大尺度原子、分子团簇电子和几何结构的理论研究
核子自旋结构与高能反应过程的自旋不对称
  • 批准号:
    10975092
  • 项目类别:
    面上项目
  • 资助金额:
    40.0万元
  • 批准年份:
    2009
  • 负责人:
    梁作堂
  • 依托单位:
非线性抛物双曲耦合方程组及其吸引子
  • 批准号:
    10571024
  • 项目类别:
    面上项目
  • 资助金额:
    23.0万元
  • 批准年份:
    2005
  • 负责人:
    秦玉明
  • 依托单位: