A systems approach to combat the significant antibiotic resistance challenge: Novel therapeutic strategies, mechanistic discoveries, and drug development
A systems approach to combat the significant antibiotic resistance challenge: Novel therapeutic strategies, mechanistic discoveries, and drug development
批准号:
nhmrc : GNT1157909
负责人:
Prof Jian Li
金额:
$78.54万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 --
中文摘要
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英文摘要
Antibiotic-resistant ‘superbugs’ are a significant global medical challenge. Polymyxins are the only effective antibiotics against Gram-negative bacteria, although limited pharmacological data are available for their optimal use. In the next 5 years, I will re-develop polymyxins and discover novel antibiotics against high-priority pathogens. My research targets the “Bad Bugs, No Drugs” unmet medical need highlighted by the World Health Organization and The Infectious Diseases Society of America.
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会议论文
Targeting the unmet global medical need caused by Gram-negative 'superbugs': from antibiotic discovery to novel therapeutic strategies
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批准号:nhmrc : 1063069
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项目类别:Research Fellowships
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资助金额:$46.49万
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财政年份:2014
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负责人:Prof Jian Li
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依托单位:
Bad Bugs Need Drugs: combating antibiotic resistance caused by bacterial ‘superbugs’
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批准号:nhmrc : GNT1063069
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项目类别:Research Fellowships
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财政年份:2014
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负责人:Prof Jian Li
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依托单位:
Combating the global medical challenge caused by Gram-negative 'superbugs': from redeveloping the polymyxins to discovering novel antibiotics
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批准号:nhmrc : 1002788
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项目类别:NHMRC Research Fellowships
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资助金额:$25.01万
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财政年份:2011
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负责人:Prof Jian Li
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依托单位:
Targeting an impending global disaster: the mismatch between increasingly drug-resistant superbugs and development of new antibiotics
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批准号:FT100100002
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项目类别:ARC Future Fellowships
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资助金额:$0.0万
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财政年份:2010
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负责人:Prof Jian Li
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依托单位:
Keeping colistin active against superbugs: From laboratory to ward, from pharmacology to commercial products
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批准号:nhmrc : 465119
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项目类别:Career Development Fellowships
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资助金额:$26.52万
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财政年份:2007
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负责人:Prof Jian Li
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依托单位:
国内基金
海外基金
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