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Open Network for WAter-Related Diseases (ONWARD)

Open Network for WAter-Related Diseases (ONWARD)
水相关疾病开放网络 (ONWARD)
批准号:
EP/T003820/1
负责人:
T Platt
金额:
$19.34万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2020
资助国家:
英国
项目状态:
已结题
起止时间:
2020 至 --

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中文摘要
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英文摘要
The ONWARD Network (Open Network for Water-Related Diseases) is dedicated to forecasting, early warning and risk mapping for water-associated diseases through use of remote sensing, field observations and mathematical modelling. Our vision is to enable cost-effective, regularly updated, geo-referenced early warning for areas vulnerable to water-associated diseases, which in turn will enable preventive measures to be deployed in a timely manner to minimise the probability of epidemics. Our long-term vision is to establish a system that will be applicable broadly, in a variety of localities and for a variety of diseases.By "water-associated" disease, we mean a rather broad class, including diarrhoeal diseases such as cholera; skin diseases associated with water-borne bacteria or metazoan parasites; vector-borne diseases such as malaria and dengue fever; and others such as hepatitis. Any or all of them will be relevant to the activities of the network. The "water" involved may be fresh, or brackish or coastal seawater. The network will respond primarily the GCRF Challenge of Global Health (infectious diseases), and secondarily to that of Resilience to Environmental Shocks and Change (since outbreaks of water-associated diseases are affected by extreme weather events, expected to become more frequent as a result of climate change). The network will also address UN Sustainable Development Goal 3, Target 3d, to "Strengthen the capacity of all countries, in particular developing countries, for early warning, risk reduction and management of national and global health risks." According to the World Health Organisation, some two billion people use faecally-contaminated drinking water, putting them at risk of death or chronic poor health from water-borne infectious diseases such as cholera, dysentery, typhoid and polio. Provision of safe drinking water is hostage to the influence of extreme weather and flooding. Apart from the fatalities, the effect of a chronic burden of lower-level infection by water-associated diseases is antagonistic to the maintenance of a healthy work force and to the well-being of society in general, to the detriment of sustainable development. For example, cholera kills an estimated 95,000 people every year, but it also makes another 2.9 million seriously ill with a debilitating disease. Hence the need to address, in addition, the resilience of communities to perturbations of the safe drinking water supply under extreme weather events associated with a changing climate.Before now, our ability to develop early warning, risk reduction and management of national and global health risks due to water-associated diseases has been limited by mutual isolation of the scientific communities whose collective effort is required to make progress. Forecasting outbreaks of water-associated diseases and their geo-referenced risk mapping is a complex matter for which the collaboration of experts from several disciplines (ranging from environmental biochemistry, genetics, molecular biology, social sciences and epidemiology to remote sensing and modelling) is needed if we are to make real advances. Hitherto, the required experts have rarely encountered each other in a scientific setting. A multidisciplinary network is essential to foster exchange of ideas between them, and so build a collaborative approach to a difficult problem by uniting them behind a common target. We believe that progress in early warning, risk forecasting and risk management of water-associated diseases will be possible through the combined efforts of specialists in the stated disciplines. Establishment of a related network is the perfect way to bring this about. An international team of outstanding experts, as well as related stakeholders, has been assembled to undertake the work. The network will be an open one. As well as the research activity, there will be a component of capacity building delivered through two training courses.
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国内基金
海外基金
丝氨酸/甘氨酸/一碳代谢网络(SGOC metabolic network)调控炎症性巨噬细胞活化及脓毒症病理发生的机制研究
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    81930042
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    重点项目
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    305.0万元
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    2019
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    王迪
  • 依托单位:
多维在线跨语言Calling Network建模及其在可信国家电子税务软件中的实证应用
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  • 项目类别:
    重大研究计划
  • 资助金额:
    170.0万元
  • 批准年份:
    2014
  • 负责人:
    郑庆华
  • 依托单位:
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    60673142
  • 项目类别:
    面上项目
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  • 批准年份:
    2006
  • 负责人:
    罗惠琼
  • 依托单位: