CANCER AND LEUKEMIA GROUP B

本申请寻求对拉丁美洲和加勒比法律援助组织活动的支持， 加州大学的研究人员 圣地亚哥医学院和附属机构，在 癌症和白血病小组B的项目。 期间 下一个资助期，我们的目标是作出重大贡献， 集团权责发生制、集团科学和集团管理。 我们 预计由于活动增加，应计费用会有所增加 无论是在主要成员机构和我们的律师，与一个 第一年的最低目标是200例 应用程序. 我们希望继续为以下方面作出广泛贡献： 集团的智力生产力，通过设计和主持 协议，提出试点意见，供集团验证， 扩大，并通过刺激更多的基础研究组成部分， 团体活动。 我们计划继续为集团提供直接服务 通过维持有效的细胞表面标记参考， 具有极高的技术质量和科学 复杂性，并使用新技术， 实验室，以进一步扩大组科学。 的市民 各机构期望继续对小组作出重大贡献 科学/行政作为主席（Seagren -辐射模态 委员会;约翰逊-数据管理委员会;绿色- 呼吸系统疾病委员会）或副主席（罗伊斯顿- 免疫学委员会）或核心委员会成员 集团科学和行政委员会。 我们将继续 作为CCOP的临床资源和研究基地 我们的CCOP附属机构在内华达州拉斯维加斯的活动， 致力于进一步加强我们的临床试验 网络作为一种手段，既增加应计利润， 增强智力活力和先进性 在整个圣地亚哥地区提供全面的肿瘤治疗。 继续参与拉丁美洲和加勒比地区法律援助和指导委员会， 重要的教育工具，教师，研究员，和 加州大学圣地亚哥分校，退伍军人管理局医疗 中心，海军地区医疗中心，以及所有 血液学私人执业的附属参与者， 参与我们CALGB活动的医学肿瘤学专家。

This application seeks support for the activities of CALGB investigators participating through the University of California San Diego School of Medicine and adjunct institutions, in the programs of the Cancer and Leukemia Group B. During the coming grant period, we aim to make major contributions to Group accrual, Group science, and Group administration. We project some increase in accrual based on enhanced activities both at the main member institution and in our adjuncts, with a minimum goal of 200 accuerd cases in the first year of this application. We expect to continue to contribute extensively to intellectual productivity of the Group by designing and chairing protocols, presenting pilot observations for Group validation and expansion, and by stimulating more basic research components to Group activities. We plan to continue direct service to the Group by maintaining an active Cell Surface Marker Reference Laboratory of exceptionally high technical quality and scientific sophistication, and use new techniques available within that laboratory to further broaden Group science. Members of our institution expect to continue their major contributions to Group science/administration as chairs (Seagren - Radiation Modality Committee; Johnson - Data Management Committee; Green - Respiratory Disease Committee) or vice-chairs (Royston - Immunology Committee) or Core Committee members of standing Group scientific and administrative committees. We will continue to serve as a clinical resource and research base for CCOP activities of our CCOP adjunct in Las Vegas, Nevada, and are working to further strengthen our clinical trials Outreach Network as a means to both increase accrual and stimulate and strengthen the intellectual vitality and state-of-the-art quality of overall oncology care delivered in the entire San Diego area. Ongoing participation in CALGB continues to serve as an important educational vehicle for Faculty, Fellows, and Housestaff at UCSD, the Veterans Administration Medical Center, the Naval Regional Medical Center, as well as for all the affiliated participants in private practice of hematology and medical oncology who share in our CALGB activities.