COOPERATIVE CLINICAL RESEARCH

合作临床研究

• 批准号: 3558913
• 负责人: WILLIAM M DUGAN
• 金额: $ 17万
• 依托单位: INDIANA UNIVERSITY HEALTH, INC.
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-09-01 至 1993-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3558913
• 关键词: cancer information system; cancer registry /resource; cancer rehabilitation /care; clinical trials; community health services; cooperative study; early diagnosis; hospices; human subject; human therapy evaluation; medical outreach /case finding; monoclonal antibody; neoplasm /cancer chemotherapy; neoplasm /cancer diagnosis; neoplasm /cancer education; neoplasm /cancer immunotherapy; neoplasm /cancer surgery; neoplasm /cancer therapy; patient /disease registry; pediatric neoplasm /cancer; rural area

This application represents the offer of the Cancer Center, Methodist Hospital of Indiana, Inc. (MHI) to develop, implement, and sustain a Community Clinical Oncology Program (CCOP) in one of the largest geographical areas not yet served by a COOP. MHI is the thirteenth largest nonprofit private general hospital in the nation and the largest cancer service in Indiana with 1,606 new cases per year. The major substantive features of this proposal are as follows: (1) a solid, experienced group of 20 practicing cancer physicians. (2) a sophisticated, smoothly functioning 8000-sq-ft clinical cancer research center, an annual budget of $442,361, and 11 employees. (3) significant dedicated institutional resources to cancer. A cancer programmatic commitment of more than $6 million this year, an administrative cancer commitment of $988,000, which includes a MHI CCOP match of $41,810 to staff compensation. (4) the enthusiastic support for CCOP from the cancer doctors, the medical staff, the hospital administrative staff, the Indiana State Board of Health, the National Medical Association, MetroHealth HMO, Eli Lilly Co., and 21 network hospitals. (5) the ability to accrue 120 credits/year to Eastern Cooperative Oncology Group (ECOG), National Surgical Adjuvant Breast and Bowel Project (NSABP), Children's Cancer Study Group (CCSG), and M.D. Anderson Cancer Center (MDACC) clinical trials and cancer research protocols. . Total NCI treatment research accrual for 1988 at 29, for 1989 at 24 (six months). . Significant cancer research experience with more than 30 publications and 400 patients accrued to in-house protocols over the past eight years, including 48 patients accrued in the last 66 weeks to non-competitive Eli Lilly Phase I studies. . Significant cancer control experience and cancer control research background. Over the past eight years more than 500 patients have been accrued to cancer control research studies in addition to 1400 patients enrolled in a luxograhy screening project. The total NCI cancer control research accrual for 1989 is 43 (six months). (6) a unique comprehensive network program with access to underserved rural communities with 3029 projected new cancer cases in 1989 and two HMOs with a total of 87,000 enrollees which could serve as target groups for cancer control research activities. (7) access to a large minority population in Indianapolis. (8) a defined organizational structure with goals, objectives, policies, procedures and staffing in place. A hospital finance department with significant experience in NIH/NCI contract/grant management. An academic component with 150 house staff and 100 medical students at any one time. With experienced investigators, a substantial patient base, significant cancer control research experience, solid clinical research experience, and strong administrative and staff commitments, MHI can serve as a major addition to NCI CCOP.

本申请由卫理公会癌症中心提供 印第安纳医院(MHI)开发、实施和维持 社区临床肿瘤学计划(CCOP)是最大的社区临床肿瘤学计划之一 还没有鸡舍服务的地理区域。三菱重工是全球第13大 全国非营利性私立综合医院和最大的癌症 在印第安纳州服务，每年有1,606个新病例。 这项提议的主要实质性特点如下： (1)由20名执业癌症医生组成的扎实、经验丰富的团队。 (2)功能完善的8000平方英尺临床癌症 研究中心，年度预算442,361美元，11名员工。 (3)大量专门用于癌症的机构资源。一种癌症 今年超过600万美元的计划承诺， 988,000美元的癌症行政承诺，其中包括三菱重工CCOP 41,810美元与工作人员薪酬相匹配。 (4)癌症医生、医学界对CCOP的热情支持 工作人员，医院行政人员，印第安纳州委员会 健康，国家医学会，MetroHealth HMO，礼来公司， 和21家网络医院。 (5)东部合作肿瘤学每年获得120学分的能力 国家外科辅助乳肠计划组(ECOG)， 儿童癌症研究小组(CCSG)和M.D.安德森癌症中心 (MDACC)临床试验和癌症研究方案。 。NCI治疗研究的总应计费用1988年为29,1989年为24(6 月)。 。拥有30多份出版物和重要的癌症研究经验 在过去的八年里，400名患者接受了内部治疗方案， 包括在过去66周内因非竞争性ELI而累积的48名患者 礼来公司第一阶段研究。 。重要的癌症控制经验和癌症控制研究 背景资料。在过去的八年里，超过500名患者被 除了1400名患者外，还应计入癌症控制研究 参加了一个奢华的电影放映项目。NCI癌症总体控制 1989年的应计研究费用为43美元(6个月)。 (6)独特的综合网络计划，可进入服务不足的农村地区 1989年预计有3029例新癌症病例的社区和两个HMO 共有8.7万名参与者可能成为癌症的目标群体 控制研究活动。 (7)进入印第安纳波利斯的大量少数族裔人口。 (8)明确的组织结构，包括目标、目标、政策、 程序和人员配备到位。一家医院的财务部 在NIH/NCI合同/赠款管理方面有丰富经验。一位学者 任何时候都有150名宿舍工作人员和100名医科学生。 拥有经验丰富的调查人员，坚实的患者基础，意义重大 癌症控制研究经验，扎实的临床研究经验，以及 强有力的行政和员工承诺，三菱重工可以作为一个主要的 添加到NCI CCOP。