COOPERATIVE CLINICAL RESEARCH

合作临床研究

• 批准号: 3558917
• 负责人: WILLIAM M DUGAN
• 金额: $ 17.16万
• 依托单位: INDIANA UNIVERSITY HEALTH, INC.
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-09-01 至 1993-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3558917
• 关键词: cancer information system; cancer registry /resource; cancer rehabilitation /care; clinical trials; community health services; cooperative study; early diagnosis; hospices; human subject; human therapy evaluation; medical outreach /case finding; monoclonal antibody; neoplasm /cancer chemotherapy; neoplasm /cancer diagnosis; neoplasm /cancer education; neoplasm /cancer immunotherapy; neoplasm /cancer surgery; neoplasm /cancer therapy; patient /disease registry; pediatric neoplasm /cancer; rural area

This application represents the offer of the Cancer Center, Methodist Hospital of Indiana, Inc. (MHI) to develop, implement, and sustain a Community Clinical Oncology Program (CCOP) in one of the largest geographical areas not yet served by a COOP. MHI is the thirteenth largest nonprofit private general hospital in the nation and the largest cancer service in Indiana with 1,606 new cases per year. The major substantive features of this proposal are as follows: (1) a solid, experienced group of 20 practicing cancer physicians. (2) a sophisticated, smoothly functioning 8000-sq-ft clinical cancer research center, an annual budget of $442,361, and 11 employees. (3) significant dedicated institutional resources to cancer. A cancer programmatic commitment of more than $6 million this year, an administrative cancer commitment of $988,000, which includes a MHI CCOP match of $41,810 to staff compensation. (4) the enthusiastic support for CCOP from the cancer doctors, the medical staff, the hospital administrative staff, the Indiana State Board of Health, the National Medical Association, MetroHealth HMO, Eli Lilly Co., and 21 network hospitals. (5) the ability to accrue 120 credits/year to Eastern Cooperative Oncology Group (ECOG), National Surgical Adjuvant Breast and Bowel Project (NSABP), Children's Cancer Study Group (CCSG), and M.D. Anderson Cancer Center (MDACC) clinical trials and cancer research protocols. . Total NCI treatment research accrual for 1988 at 29, for 1989 at 24 (six months). . Significant cancer research experience with more than 30 publications and 400 patients accrued to in-house protocols over the past eight years, including 48 patients accrued in the last 66 weeks to non-competitive Eli Lilly Phase I studies. . Significant cancer control experience and cancer control research background. Over the past eight years more than 500 patients have been accrued to cancer control research studies in addition to 1400 patients enrolled in a luxograhy screening project. The total NCI cancer control research accrual for 1989 is 43 (six months). (6) a unique comprehensive network program with access to underserved rural communities with 3029 projected new cancer cases in 1989 and two HMOs with a total of 87,000 enrollees which could serve as target groups for cancer control research activities. (7) access to a large minority population in Indianapolis. (8) a defined organizational structure with goals, objectives, policies, procedures and staffing in place. A hospital finance department with significant experience in NIH/NCI contract/grant management. An academic component with 150 house staff and 100 medical students at any one time. With experienced investigators, a substantial patient base, significant cancer control research experience, solid clinical research experience, and strong administrative and staff commitments, MHI can serve as a major addition to NCI CCOP.

此应用程序代表的癌症中心，卫理公会的报价 印第安纳州医院，公司(MHI)制定、实施和维持一个 社区临床肿瘤学计划（CCOP）是世界上最大的 地理区域尚未被COOP服务。 三菱重工是第十三大 全国最大的非营利性私立综合医院， 在印第安纳州，每年有1,606例新病例。 该提案的主要实质性特点如下： (1)一个由20名经验丰富的癌症执业医生组成的坚实团队。 (2)一个复杂的，功能平稳的8000平方英尺的临床癌症 研究中心，年预算442，361美元，11名员工。 (3)为癌症投入了大量的专门机构资源。 癌症 今年的方案承诺超过600万美元， 行政癌症承诺988，000美元，其中包括MHI CCOP 41 810美元与工作人员补偿金相匹配。 (4)来自癌症医生、医学界和社会各界的热情支持， 工作人员，医院行政人员，印第安纳州州委员会， 健康，国家医学协会，大都会健康HMO，礼来公司， 21家网络医院 (5)每年向东部肿瘤合作组织累积120个学分的能力 国家乳腺和肠道手术辅助项目（NSABP）小组（ECOG）， 儿童癌症研究小组（CCSG）和医学博士。安德森癌症中心 （MDACC）临床试验和癌症研究方案。 . 1988年NCI治疗研究累计总数为29，1989年为24（6 月）。 .重要的癌症研究经验，发表论文30多篇， 在过去的八年里，有400名患者加入了内部协议， 包括48例在过去66周内接受非竞争性Eli 礼来I期研究。 .重要的癌症控制经验和癌症控制研究 背景 在过去的八年里，有500多名患者 除了1400名患者外， 参加了一个luxograhy筛查项目 NCI癌症控制总 1989年应计研究费用为43美元（6个月）。 (6)一个独特的综合网络计划， 1989年预计有3029例新发癌症病例的社区和 共87，000名参加者可作为癌症的目标群体 控制研究活动。 (7)印第安纳波利斯的少数民族人口 (8)一个明确的组织结构，包括目标、目的、政策， 程序和人员配置到位。 一家医院财务部， 在NIH/NCI合同/赠款管理方面有丰富经验。 一个学术 在任何时候都有150名内部工作人员和100名医学生。 凭借经验丰富的研究人员，大量的患者基础， 癌症控制研究经验，扎实的临床研究经验，以及 强大的行政和工作人员的承诺，MHI可以作为一个主要的 加入NCI CCOP。