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TYROSINE PHOSPHATASES AND INSULIN RESISTANCE IN THE AGED

TYROSINE PHOSPHATASES AND INSULIN RESISTANCE IN THE AGED
老年人的酪氨酸磷酸酶和胰岛素抵抗
批准号:
3802217
负责人:
M BERNIER
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:

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中文摘要
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英文摘要
This is a new project that is aimed at defining insulin resistance to the aging process with the long term goals of developing therapeutic interventions. Synthetic peptides have been made based on the sequence of the insulin receptor beta-subunit in an attempt to prepare an affinity matrix suitable for the purification and characterization of tyrosine protein phosphatase activity that has high specificity toward the insulin receptor. The significance of the project lies in the identification of such insulin receptor-specific phosphatase(s) in intact cell, as well as in the characterization of insulin resistance secondary to variation phosphatase activity.
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ARGININE AND INSULIN RESPONSE IN ADIPOCYTES
  • 批准号:
    5200374
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    M BERNIER
  • 依托单位:
TYROSINE PHOSPHATASES AND INSULIN RESISTANCE IN THE AGED
  • 批准号:
    3789774
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    M BERNIER
  • 依托单位:
GLUCOSE SIGNALING AND REGULATION OF GENE EXPRESSION IN 3T3-L1 ADIPOCYTES
  • 批准号:
    2565787
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    M BERNIER
  • 依托单位:
ALKYLATION OF SULFHYDRYL GROUP(S) ON THE INSULIN RECEPTOR ALTER KINASE ACTIVITY
  • 批准号:
    3745570
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    M BERNIER
  • 依托单位:
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