HEPARIN METABOLISM IN THE NEWBORN

新生儿的肝素代谢

• 批准号: 3903889
• 负责人: WILLIAM E HATHAWAY
• 金额: --
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3903889
• 关键词: antithrombin III; blood chemistry; blood coagulation tests; carbohydrate metabolism; dosage; drug administration routes; drug metabolism; drug tolerance; gestational age; heparin; human pregnant subject; human subject; injection /infusion; newborn human (0-6 weeks); pediatric pharmacology; thrombosis

Pharmacokinetics of intravenous heparin will be studied in newborn infants of various ages. Both clotting and chromogenic assays for heparin and AT-III heparin cofactor will be used.

将在新生儿中研究静脉注射肝素的药代动力学 不同年龄的婴儿。 凝血和显色试验 将使用肝素和AT-III肝素辅因子。