REDOX PROTEINS AND THEIR MODEL

我们提议的项目的主要目标是调查 蛋白质、核酸等的电荷转移机制 模型化合物。调查人员还计划研究照片- 界面处的感应电荷转移过程 蛋白质组织和芳香烃的研究 致癌。 氧化还原蛋白的异相电荷转移机制， 如马心细胞色素C(Cyt C)和铁氧还蛋白 在不同的电极上进行检查。电化学法 包括循环伏安法、方波伏安法 (SWV)和计时库仑原位拉曼光谱 用来获得这些蛋白质的结构信息 氧化和还原过程中的分子。 光致电荷转移(或能量转移) 组织中的蛋白质和芳香族碳氢化合物，如芳烃 并用荧光法研究了荧蒽 光谱学，以及稳态荧光研究 系统。 这项研究可以为启蒙提供信息。 芳香族碳氢化合物与苯环间的致癌反应 蛋白质组织。

The main objective of our proposed project is to investigate charge transfer mechanism of proteins, nucletic acids and other model compounds. The investigators also plan to study photo- induced charge transfer processes at the interface between protein tissue and aromative hydrocarbons for the investigation of carcinogenesis. The heterogeneous charge transfer mechanism of redox proteins, such as horse heart cytochrome C (Cyt C) and ferredoxin will be examined at various electrodes. Electrochemical methods including cyclic voltammetry (CV), square wave voltammetry (SWV) and chronocoulometry Situ Raman spectroscopy will be utilized to obtain structural information of those protein molecules during the oxidation and reduction processes. Photo-induced charge transfer (or energy transfer) between proteins of tissue and aromatic hydrocarbons, such as perylene and fluoranthene will be investigated by fluorescence spectroscopy, as well a steady state fluorescence studies of the systems. This study may provide the information for the initiation reactions of carcinogenesis between aromatic mydrocarbons and protein tissue.