INSIGHT - medIcal oxygen supply chaiN deSIGn and planning for COVID-19 HospiTals

随着正在进行的SARS-CoV-2大流行的演变变得越来越不确定，氧气治疗是目前患者的主要治疗方法，确保医疗氧气供应链的弹性和稳健运行变得越来越紧迫。INSIGHT将针对当前和未来的SARS-CoV-2浪潮以及需要应急规划的其他流行病和病例，对英国医用氧气供应链的综合设计和运营进行全系统分析。INSIGHT的一个关键独特性是供应链的空间明确和不确定性建模，这将为应对未来COVID-19浪潮的不同实现提供区域特定战略的路线图。我们为加强应急规划决策制定而制定的基于优化的框架将是开源的、可公开获得的，而且由于INSIGHT的设计，可以很容易地推广，为欧洲和中低收入国家（LMICs）的战略提供信息。为此，我们建议将供应链优化、多尺度建模和随机优化的方法结合起来。通过我们与林德的长期合作。我们一直在开发与空分行业相关的PLC模型。最后，我们已经确保了中国银行的积极参与，这是两家nhs大宗医用氧气供应商之一，以便最大限度地发挥INSIGHT结果的影响力和适用性。

With the evolution of the ongoing SARS-CoV-2 pandemic becoming increasingly uncertain andoxygen-therapy being the current dominant treatment of patients, securing resilient and robustoperation of medical oxygen supply chains becomes increasingly urgent. INSIGHT will develop a whole-systems analysis on the integrated design and operation of medical oxygen supply chains inthe UK for current, future waves of SARS-CoV-2 as well as for other pandemics and cases thatrequire emergency planning. A key uniqueness of INSIGHT is the spatially-explicit and uncertainty-awaremodelling of supply chains which will provide a roadmap to region-specific strategies forcoping with different realisations of future COVID-19 waves. Our optimisation-based framework for enhanced decision making for emergency planning will be open-source, publicly available anddue to the design of INSIGHT could be easily generalised to inform European and low and middle incomecountries (LMICs) strategies. To this end, we propose to combine methodologies fromsupply chain optimisation, multi-scale modelling and stochastic optimisation. Throughour long-standing collaboration with Linde.plc we have been developing models related to the airseparation industry. Finally, we have secured the active participation of BOC, one of the two NHSbulk medical oxygen providers, so as to maximise the impact and applicability of INSIGHT'soutcomes.