LDH-C4 抑制剂作为男性避孕药的测试-猫眼课题宝

LDH-C4 抑制剂作为男性避孕药的测试

批准号：

3653286

负责人：

MITCHELL AVERY

金额：

$14.47万

依托单位：

SRI INTERNATIONAL

依托单位国家：

美国

项目类别：

财政年份：

1987

资助国家：

美国

项目状态：

已结题

起止时间：

1987-12-01 至 1990-11-30

来源：

https://reporter.nih.gov/project-details/3653286

关键词：

drug design /synthesis /production drug screening /evaluation enzyme inhibitors isozymes lactate dehydrogenases spermicide

中文摘要

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英文摘要

The proposed research is a comprehensive, 36 month, synthetic and biological testing program aimed at the development of novel non-steroidal male contraceptive agents that will adversely affect the progress of sperm maturation, as well as have a lethal effect on mature spermatozoa. It will prove that the proposed compounds will behave as specific inhibitors of LDH-C4, and in turn, will be effective and safe male contraceptive agents.

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