DEVELOP METHODS OF ANALYSIS OF HUMAN COLOSTRUM AND MILK

开发人初乳和乳汁的分析方法

• 批准号: 3652211
• 负责人: TOMAS R GUILARTE
• 金额: $ 6.45万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-02-01 至 1989-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3652211
• 关键词: analytical chemistry; biotin; colostrums; human milk; human tissue; niacin; nutrition related tag; radioassay; thiamine; vitamin B complex; vitamin B6

The analysis of vitamin B in human milk and colostrum is greatly complicated by the lack of modern methodologies available as well as the large number of B vitamers present in these fluids. This project will develop a radiometric microbiological assay for vitamin B-6 and niacin to complete the development of similar assay procedures for thiamin, biotin, and pantothenic acid in these fluids. Specifically, the project will: 1) apply already developed RMA for vitamin B-6 and niacin for the anlaysis of these vitamins in human colostrum and milk. 2) complete the development and validation of RMA's for thiamin, biotin, and pantothenic acid and apply the RMA's in the analysis of these vitamins in human colostrum and milk.

人乳和初乳中维生素B的分析大大提高了 由于缺乏可用的现代方法， 这些液体中含有大量的B族维生素。 该项目将 开发维生素B-6和烟酸的放射性微生物测定法， 完成硫胺素，生物素， 和泛酸。 具体而言，该项目将： 1)应用已开发的维生素B-6和烟酸RMA进行分析 这些维生素在人类初乳和牛奶中的含量。 2)完成硫胺素，生物素， 和泛酸，并将RMA应用于这些维生素的分析 在人类初乳和乳汁中。