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Control of Immunoreceptor Assembly and Function by Intramembrane Sequence Elements

Control of Immunoreceptor Assembly and Function by Intramembrane Sequence Elements
膜内序列元件对免疫受体组装和功能的控制
批准号：
nhmrc : 1011352
负责人：
A/Pr Matthew Call
金额：
$26.88万
依托单位：
The Walter and Eliza Hall Institute of Medical Research
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2011
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2011-01-01 至 2013-12-31
来源：
https://researchdata.edu.au/control-immunoreceptor-assembly-sequence-elements/109577
关键词：
ControlImmunoreceptorAssemblyFunctionIntramembrane

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中文摘要
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英文摘要
The cells of the immune system constantly survey their environment for changes that indicate damage. To sense their surroundings cells employ a host of receptors that are associated with signalling adapter proteins that initiate signalling cascades inside the cell when receptors bind ligands. This project seeks to determine the structural mechanisms of signal propagation across the plasma membrane of immune cells.
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Structural Basis of Substrate Recognition by the Membrane-Associated E3 Ubiquitin Ligases
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