INTERNATIONAL EPIDEMIOLOGY SURVEY OF HUMAN RETROVIRUSES

人类逆转录病毒国际流行病学调查

• 批准号: 2591818
• 负责人: HILLARY R KRUGER
• 金额: $ 45万
• 依托单位: RESEARCH TRIANGLE INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-03-01 至 1998-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2591818
• 关键词: Retroviridae; Retroviridae disease; blood banks; cancer risk; data collection methodology /evaluation; health science research support; health surveys; human tissue; medical records; neoplasm /cancer epidemiology; tissue resource /registry

The Viral Epidemiology Branch of the National Cancer Institute undertakes a broad range of epidemiologic studies of cancer and AIDS causing viruses with a particular emphasis on Human Immunodeficiency Virus and other oncogenic retroviruses. Many of these viruses occur in overseas locales such as the human T-cell lymphotrophic viruses type I and II. The objective of the proposed contract will be to support the research mission of the Viral Epidemiology Branch by facilitating overseas research projects whose goals are defined by Viral Epidemiology Branch staff. These studies often take place in settings where communications, and access to study populations are limited because they are in developing countries in Africa, Asia, and Central and South America. A major object of the proposed contract will be to supports these studies by facilitating access to populations, arranging for cooperation with local medical and governmental health officials. Another objective is for the contractor to insure that all clearances are obtained from appropriate Institutional Review Boards to insure that all requirements of the Office for Protection from Research Risk are fulfilled. Another objective will be for the contractor to implement research protocols originated by Viral Epidemiology Branch staff and insure that special circumstances in the local environment such as special logistical concerns, cultural sensitivities, etc are addressed. The major objective is for the contractor to implement overseas field work in a way that insures that the data and samples collected are of the highest quality for epidemiologic analysis. Another objective is for the contractor to supply NCI with data that can be analyzed by the Viral Epidemiology Branch with results of studies to be published in peer review journals. In summary the objective of this project is to conduct a series of epidemiologic studies of human retroviruses in different geographic locales to answer scientific questions concerning the role of these and other oncogenic viruses in the etiology of cancer.

美国国家癌症研究所病毒流行病学分部承担 对引起癌症和艾滋病的病毒进行广泛的流行病学研究 特别强调人类免疫缺陷病毒和其他 致癌逆转录病毒。 其中许多病毒发生在海外地区 例如人类T细胞淋巴病毒I型和II型。 这 拟议合同的目标是支持研究 病毒流行病学分会的使命是促进海外 其目标由病毒流行病学分支确定的研究项目 职员。 这些研究通常发生在通信、 并且接触研究人群的机会有限，因为他们处于 非洲、亚洲、中南美洲的发展中国家。 一个 拟议合同的主要目标是支持这些研究 通过便利接触民众、安排与 当地医疗和政府卫生官员。 另一个目标是 承包商确保所有许可均获得 适当的机构审查委员会以确保所有要求 研究风险保护办公室的职责已履行。 其他 目标是让承包商实施研究协议 由病毒流行病学部门工作人员发起，并确保特殊 当地环境的情况，例如特殊的物流 关切、文化敏感性等得到解决。 主要目标 承包商以以下方式实施海外现场工作： 确保收集的数据和样本具有最高质量 用于流行病学分析。 承包商的另一个目标是 向 NCI 提供可通过病毒流行病学分析的数据 分支的研究结果将在同行评审期刊上发表。 总之，该项目的目标是进行一系列 不同地区人类逆转录病毒流行病学研究 场所来回答有关这些作用的科学问题 癌症病因学中的其他致癌病毒。