PHASE III RANDOMIZED STUDY OF CISPLATIN VS TAXOL VS TAXOL AND CISPLATIN

顺铂 VS 紫杉醇 VS 紫杉醇和顺铂的 III 期随机研究

• 批准号: 3740350
• 负责人: HARRISON G BALL
• 金额: --
• 依托单位: TUFTS MEDICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3740350
• 关键词: cis platinum compound; clinical trials; combination chemotherapy; human subject; human therapy evaluation; neoplasm /cancer chemotherapy; ovary neoplasms; paclitaxel

The objective of this study is to determine the relative efficacy of regimens consisting of taxol, versus cisplatin and versus a combination of the two drugs in patients with suboptimally debulked epithelial ovarian cancer; to determine which of the three regimens contribute most favorably to progression-free interval and survival ; to compare the incidence of the audiologic sequelae and other toxicities arising from either of the three regimens.

本研究的目的是确定其相对疗效。 紫杉醇、顺铂和联合用药组成的方案 两种药物在次优上皮损伤患者中的作用 卵巢癌；确定三种方案中哪种方案见效最大 有利于无进展间期和生存期；比较 听力学后遗症和其他毒性反应的发生率 三种养生法中的一种。