PULMONARY FUNCTION AND BRONCHIAL RESPONSIVENESS IN INFANTS WITH LUNG DISEASE

患有肺病的婴儿的肺功能和支气管反应性

• 批准号: 3740848
• 负责人: FRANK J ACCURSO
• 金额: --
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3740848
• 关键词: bronchodilators; cystic fibrosis; human subject; human therapy evaluation; infant human (0-1 year); inhalation drug administration; longitudinal human study; pediatric pharmacology; respiratory disorder chemotherapy; respiratory function; respiratory pharmacology; respiratory therapy

We propose to perform a longitudinal study in infants with cystic fibrosis (CF), to prospectively examine pulmonary function and the development of bronchial responsiveness to inhaled albuterol. These studies will provide insight into the pathophysiology of CF in infants and aid in evaluating the acute effects of these inhalation treatments.

我们建议对患有囊性病变的婴儿进行纵向研究。 肺纤维化（CF），前瞻性检查肺功能和 对吸入沙丁胺醇的支气管反应性的发展。 这些 研究将提供对婴儿CF病理生理学的深入了解 并有助于评估这些吸入治疗的急性效应。