EFFECTS OF MANNITOL ON DIALYSIS INDUCED MUSCLE CRAMPS

骨骼肌痉挛是一种常见的和麻烦的并发症， 血液透析。标准治疗包括静脉注射 高渗盐水、甘露醇或氯化钙。甘露醇似乎 对治疗抽筋最有效 此外据指出 附带地，在一项研究中， 血液透析期间使用甘露醇可减少近50%的痉挛。尽管如此 有证据表明，甘露醇在这组患者中使用较少，因为 担心它潜在的长半衰期。

Skeletal muscle cramps are a frequent and troublesome complication of hemodialysis. Standard treatment includes the intravenous injection of hypertonic saline, mannitol or calcium chloride. mannitol appears to be most effective in treating cramps. In addition, it was noted parenthetically in one study that prophylactic intravenous infusion of mannitol during hemodialysis reduced cramping by almost 50%. Despite this evidence, mannitol is used sparingly in this group of patients because of concerns about its potentially long half-life.