Bioactive Effective Surface For Transport Network (BEST Network)

传输网络的生物活性有效表面（BEST网络）

• 批准号: EP/X03576X/1
• 负责人: James Redfern
• 金额: $ 23.21万
• 依托单位: Manchester Metropolitan University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FX03576X%2F1
• 关键词: Bioactive; Effective; Surface; Transport; Network

The world faces many challenges, with some of the most striking relating to microorganisms, such a bacteria and viruses, small enough that you cannot see them, but with the potential to cause disease and death. Recently, it has become apparent that the effectiveness of antibiotics are reducing, meaning they are more likely to cause harm in the future. Additionally, along the recent SARS-CoV-2 viral pandemic demonstrated how quickly and widespread a microorganism can cause significant healthcare implications and harm to society. In both examples, reducing contact or exposure to these harmful microorganisms will inevitably reduce likelihood of infection. Therefore, it is sensible to consider how we can control exposure to these pathogenic microorganisms in the built environment and indoor settings. This poses particular challenges for the UK transport network, as these services are essential, and used by significant numbers of people in the UK every day. Therefore, this sector in particular requires long-term and effective solutions to inhibit pathogen transmission, providing reassurance and confidence to minimise the possible disruption to the sector in the future. Antimicrobial bioeffective surfaces (i.e. surfaces that kill/limit microorganisms) offer a great potential, but for effective use in the transport sector, a holistic approach between the transport industry, academics and other industries involved in the various disciplines regarding antimicrobial materials (e.g. advanced materials, microbiology, engineering, chemistry), as well as policy and decision makers is required. To date, there is no such network with an aim of bringing these group together to tackle the challenge of potentially pathogenic microorganisms with antimicrobial materials in the UK transport sector. It is this knowledge exchange gap that this proposed network would fulfill.

世界面临着许多挑战，其中一些最引人注目的挑战与微生物有关，如细菌和病毒，它们小到你看不见，但却有可能导致疾病和死亡。最近，很明显抗生素的有效性正在降低，这意味着它们更有可能在未来造成伤害。此外，最近的SARS-CoV-2病毒大流行表明，微生物可以迅速和广泛地造成重大的医疗保健影响和对社会的危害。在这两个例子中，减少接触或暴露于这些有害微生物将不可避免地降低感染的可能性。因此，考虑如何在建筑环境和室内环境中控制这些致病微生物的暴露是明智的。这给英国的交通网络带来了特别的挑战，因为这些服务是必不可少的，每天在英国有大量的人使用。因此，该部门尤其需要长期和有效的解决方案来抑制病原体传播，提供保证和信心，以尽量减少未来对该部门可能造成的破坏。抗菌生物有效表面（即杀死/限制微生物的表面）提供了巨大的潜力，但为了在运输部门有效使用，需要运输业、学术界和涉及抗菌材料（例如先进材料、微生物学、工程、化学）的各种学科的其他行业以及政策和决策者之间采取整体方法。迄今为止，还没有这样的网络，旨在将这些群体聚集在一起，以应对英国运输部门使用抗菌材料的潜在致病微生物的挑战。这个拟议中的网络将填补这一知识交流缺口。