PREVENTION OF RENAL STONE FORMATION IN SPACE FLIGHT

太空飞行中预防肾结石形成

• 批准号: 3742775
• 负责人: CHARLES YC PAK
• 金额: --
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3742775
• 关键词: dietary proteins; disease /disorder prevention /control; disease /disorder proneness /risk; exercise; extraterrestrial environment; human population genetics; human subject; mass screening; meat; nephrolithiasis; nutrition related tag; restricted physical activity

Overall goals are to determine if space flight confers increased risk for the formation of renal stones, and if so, establish pathogenetic factors and formulate effective countermeasures. By monitoring physiological and physicochemical effects of bedrest, pathogenetic genetic factors may be elucidated. Roles of animal protein and physical exercise will also be assessed. Astronaut candidates will be screened for stone-forming potential.

总体目标是确定太空飞行是否会增加 肾结石的形成，如果是，建立致病因素 制定有效的对策。 通过监测生理和 卧床的理化效应，致病遗传因素可能是 阐明。 动物蛋白质和体育锻炼的作用也将被 评估。 宇航员候选人将被筛选成石 潜力