SLEEP STAGE AND COLONIC MOTOR ACTIVITY IN PATIENTS WITH IRRITABLE BOWEL SYNDROME

肠易激综合征患者的睡眠阶段和结肠运动活动

• 批准号: 3743532
• 负责人: RICHARD W MCCALLUM
• 金额: --
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3743532
• 关键词: colon disorder; gastrointestinal motility /pressure; gastrointestinal sign /symptom; human subject; irritable bowel syndrome; sleep

Investigations into the mechanism of symptoms in the irritable bowel syndrome (IBS) have revealed both sensory and motor abnormalities, suggesting altered gut neural control. Normal gut neural control exists at 3 levels (CNS, ANS, and ENS) yet the level of derangement in IBS remains controversial. This study will evaluate whether the sleep stage/colon activity relation is disturbed in IBS.

肠易激症状发生机制的探讨 综合征(IBS)表现出感觉和运动的异常， 表明肠道神经控制发生了改变。存在正常的肠道神经控制 在3个水平(CNS、ANS和ENS)，IBS的排列紊乱水平 仍然存在争议。这项研究将评估睡眠是否 IBS分期/结肠活动性关系紊乱。