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EFFECT OF IV ERYTHROMYCIN AND SUBCUTANEOUS OCTREOTIDE ON ANTRO-DUODENAL MOTILITY

EFFECT OF IV ERYTHROMYCIN AND SUBCUTANEOUS OCTREOTIDE ON ANTRO-DUODENAL MOTILITY
静脉注射红霉素和皮下奥曲肽对十二指肠前运动的影响
批准号：
3743570
负责人：
RICHARD W MCCALLUM
金额：
$0.0万
依托单位：
UNIVERSITY OF VIRGINIA
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3743570
关键词：
drug screening /evaluation duodenum erythromycin gastrointestinal disorder chemotherapy gastrointestinal motility /pressure human subject human therapy evaluation intravenous administration paralysis peptide hormone analog perfusion somatostatin stomach

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英文摘要
Erythromycin has been shown to stimulate antral motility through motilin receptor stimulation, and serves as a beneficial therapy in gastroparetic patients. The effect of Octreotide on antral and small bowel motility is unclear. This study examines the effect of Erythromycin and Octreotide antroduodenal motility as measured by a hydrostatic perfusion device and electrogastrogram in patients with gastroparesis.
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