PEDIATRIC ILLNESS SEVERITY AND NITROGEN AND URIC ACID EXCRETION

儿科疾病严重程度与氮和尿酸排泄

• 批准号: 3744593
• 负责人: GREGORY A HOLLMAN
• 金额: --
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3744593
• 关键词: biomarker; child (0-11); disease /disorder proneness /risk; excretion; human morbidity; human subject; nitrogen metabolism; protein metabolism; stress; urate; urinalysis

This study will examine the relationship between illness severity, as quantified by the Pediatric Risk of Mortality Score (PRISM) and the Therapeutic Intervention Scoring System (TISS), and protein catabolism as reflected by total urine nitrogen excretion. It is anticipated that nitrogen excretion will correlate with the severity of stress response determined by these scoring systems, permitting improved nutritional monitoring and management of critically ill children.

本研究将探讨疾病严重程度，如