EFFICACY AND TOLERABILITY COMPARISON OF PROSCAR AND PLACEBO IN BPH

保列治和安慰剂治疗 BPH 的疗效和耐受性比较

• 批准号: 3743847
• 负责人: RICHARD F. SPARK
• 金额: --
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3743847
• 关键词: antineoplastics; benign prostate hyperplasia; dihydrotestosterone; drug tolerance; enzyme inhibitors; enzyme mechanism; human subject; human therapy evaluation; oxidoreductase; placebos

This protocol is designed to determine whether therapy with finasteride provides clinical improvement in patients with symptomatic BPH compared to placebo; to evaluate the tolerance of these patients to the drug; and to evaluate the effect of the drug on the 5-alpha-reductase enzymes, assessed by serum DHT.

本方案旨在确定使用芬氟拉明治疗是否 提供了症状性BPH患者的临床改善， 评估这些患者对药物的耐受性;以及 为了评价药物对5-α-还原酶的作用， 通过血清DHT评估。