Genome dynamics following plastid endosymbiosis

质体内共生后的基因组动力学

• 批准号: DP150100705
• 负责人: A/Prof Heroen Verbruggen
• 金额: $ 30.62万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-03-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP150100705
• 关键词: Genome; dynamics; following; plastid; endosymbiosis

Plastid endosymbiosis events (enslavement of an algal cell inside of a host cell to form a plastid) are difficult to pinpoint because the genomic data required for a broad array of species are rarely available. Furthermore, the classical method used to infer endosymbiotic gene transfers is being criticised. This project will elucidate the origin of chlorarachniophyte and dinoflagellate plastids and characterise the genome dynamics following endosymbiosis. It uses densely sampled genome data obtained with high-throughput sequencing technologies. Simulation studies will be used to evaluate methods for inferring endosymbiotic gene transfer and alignment-free methods will be used to improve phylogenomic pipelines.

质体内共生事件（宿主细胞内藻类细胞的奴役形成质体）很难精确定位，因为很少有广泛物种所需的基因组数据。此外，用来推断内共生基因转移的经典方法也受到了批评。本项目将阐明绿藻和甲藻质体的起源，并研究内共生后的基因组动态。它使用高通量测序技术获得的密集采样的基因组数据。模拟研究将用于评估推断内共生基因转移的方法，而无干扰方法将用于改善内共生基因管道。