Synthetic Neural Implant

合成神经植入物

• 批准号: EP/Y000226/1
• 负责人: Hagan Bayley
• 金额: $ 16.47万
• 依托单位: University of Oxford
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FY000226%2F1
• 关键词: Synthetic; Neural; Implant

The majority of neurological injuries and neurodegenerative diseases are currently untreatable with devastating health consequences and substantial financial and social burdens. Based on the technologies derived from our ERC Advanced Grant SYNTISU and a previous PoC grant BIOELECTRIC, we now aim to produce synthetic neural implants (SNIs) as a potential new treatment for patients. The SNIs will be derived from soft synthetic tissues and comprise bio-batteries and neurons. The bio-batteries will generate both electrical and ionic stimulation to stimulate diseased tissue and facilitate the integration of the SNIs and the host. The neurons will replace the damaged or dysfunctional cells and provide a compatible interface between the implant and host. We will collaborate with our industrial partner bit.bio towards the production of effective, biocompatible, robust SNIs asa marketable product, in parallel with the establishment of a new subsidiary, Bio.bio3D.

大多数神经损伤和神经退行性疾病目前无法治愈，造成毁灭性的健康后果以及巨大的经济和社会负担。基于我们的ERC Advanced Grant SYNTISU和之前的PoC Grant BioElectric获得的技术，我们现在的目标是生产合成神经植入物(SNIS)，作为一种潜在的患者新疗法。SNIS将由软合成组织衍生而来，由生物电池和神经元组成。生物电池将产生电刺激和离子刺激来刺激病变组织，并促进SNIS和宿主的整合。神经元将取代受损或功能失调的细胞，并在植入物和宿主之间提供兼容的接口。我们将与我们的工业合作伙伴BIT.BIO合作，生产有效、生物兼容、坚固的SNIS作为适销对路的产品，同时成立一家新的子公司Bio.Bio3D。