SURGERY VERSUS RADIATION THERAPY IN TREATMENT OF PRIMARY BREAST CANCER

手术与放射治疗治疗原发性乳腺癌

• 批准号: 3752327
• 负责人: J JACOBSON
• 金额: --
• 依托单位: DIVISION OF CANCER TREATMENT
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3752327
• 关键词: breast neoplasms; breast surgery; estrogen receptors; female; human mortality; human subject; human therapy evaluation; lymph nodes; neoplasm /cancer chemotherapy; neoplasm /cancer radiation therapy; neoplasm /cancer surgery; plastic surgery; postoperative state

The purpose of this study is to determine whether a breast- conserving treatment program of limited surgery and definitive radiation offers equivalent local control and survival to mastectomy in patients with early stage breast cancer. After work- up confirms localized disease, patients are randomly assigned to either primary surgery or primary irradiation. Patients treated with mastectomy are offered breast reconstruction. All patients undergo complete axillary node removal; those patients with pathological positive lymph nodes, and those with negative lymph nodes who are estrogen receptor negative receive chemotherapy.

本研究的目的是确定是否乳房-