ADJUVANT BREAST AND COLORECTAL CANCER THERAPY

此应用程序请求支持人员、运营费用和 与开展合作临床试验有关的差旅 肯塔基大学由国家外科助教组织赞助 乳房和肠道计划(NSABP)。这一支持将巩固和加强 该机构对NSABP项目已经做出了重大贡献 (在过去四年中累积了206名患者)。在露西尔·帕克酒店内 马基癌症中心，该大学开发了一个完善的框架 通过它来促进这类研究。此框架基于 临床研究办公室，协调和监测几乎所有 临床肿瘤学协议在大学，现在也作为 国家合作组织研究的行政渠道 已经在整个州的社区肿瘤学实践中被激活 肯塔基州。本提案所要求的资金是为了支持和 通过密歇根大学巩固对NSABP议定书的参与 肯塔基州计划通过(1)确保收益和卓越的持续增长 NSABP乳腺癌和结直肠癌患者的数据管理 大学，(2)为不断增长的应计和 五个附属机构的数据管理需求已经 已建立的临床研究计划；(3)提供现场数据 在当地资源匮乏的六个附属机构地点进行管理 用于监测正在研究的患者。需要大量的旅行支持 允许关键参与人员出席适当的正式会议 NSABP的指定会议。

This application requests support for personnel, operating expenses and travel related to the conduct of cooperative clinical trials at the University of Kentucky under the auspices of the National Surgical Adjuvant Breast and Bowel Project (NSABP). This support will solidify and enhance an already substantial contribution by this institution to the NSABP program (206 patients accrued over the past four years). Within the Lucille Parker Markey Cancer Center, the University has developed a sound framework through which to facilitate such studies. This framework is based in a Clinical Research Office which coordinates and monitors virtually all clinical oncology protocols at the University and now serves also as the administrative conduit through which national cooperative group studies have been activated in community oncology practices throughout the state of Kentucky. The funds requested in this proposal are to support and consolidate participation in NSABP protocols through the University of Kentucky program by (1) ensuring continued growth in accrual and excellent data management for NSABP breast and colorectal cancer patients at the University, (2) providing partial salary support for growing accrual and data management demands at five affiliate institutions with already established clinical research programs, and (3) providing on-site data management at six affiliate locations at which local resources are lacking for monitoring patients on study. Significant travel support is requested to permit key participating personnel to attend appropriate officially designated meetings of the NSABP.