PHARMACOKINETICS OF CONTROLLED RELEASE AND REGULAR FORMULATIONS OF AZT

AZT 控释和常规制剂的药代动力学

• 批准号: 3762491
• 负责人: ALAN S HOLLISTER
• 金额: --
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3762491
• 关键词: human subject; human therapy evaluation; immunopharmacology; lymphocyte; pharmacokinetics; plasma; zidovudine

The purpose of this study is to determine the plasma and intralymphocyte kinetics of zidovudine administered as a controlled release preparation compared with the current formulation of zidovudine.The study design was an open-label, randomized one week treatment, followed by crossover to the alterative formulation.

本研究的目的是测定血浆和淋巴细胞内的 齐多夫定控释制剂的药动学 与目前的齐多夫定制剂进行比较，研究设计为 一项开放标签的随机一周治疗，随后交叉至 另一种配方。