INNOBA: Infusing Nobility to Base Metals through Metal-Ligand Cooperation

INNOBA：通过金属配体合作为贱金属注入高贵性

• 批准号: EP/Y027612/1
• 负责人: Oriol Planas
• 金额: $ 25.55万
• 依托单位: Queen Mary University of London
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FY027612%2F1
• 关键词: INNOBA; Infusing; Nobility; Base; Metals

Catalysis plays a fundamental role in the efficient manufacture of all manner of products used in our daily life, but ton-scale industrial processes still rely on some of the rarest metals in the Earth's crust, such as rhodium, palladium, iridium, and platinum. The continued use of these elements represents a major challenge that must be addressed if truly sustainable chemical processes are to be developed. To tackle this issue, current strategies exploit the use of base metals (BM) and main group (MG) elements, albeit catalytic applications based on their separate use is hampered by the preference for one-electron redox events and their poorly understood redox activity, respectively. This proposal will merge the fields of coordination chemistry, organometallic synthesis, and catalysis, aiming at unveiling platforms merging the most promising properties of both strategies. With the objective of promoting and controlling two-electron events at BM centres, low-valent group 13 elements will be used to promote cooperative bond activation processes. This will allow us to infuse nobility to base metals, mimic organic transformations traditionally performed by precious metals and provide reactivity beyond them. This project will pair Al, the most abundant metal on Earth, with sustainable and highly abundant BM. Catalytic use of BM combined with subvalent Al ligands remains an uncharted territory and an exceptional opportunity to establish a new chemical space. The development of INNOBA will certainly lead to unique sustainable catalytic platforms and, eventually, a dramatic reduction of the carbon footprint of countless organic transformations currently catalysed by precious NM catalysts.

催化在我们日常生活中使用的各种产品的有效制造中起着重要作用，但吨级工业过程仍然依赖于地壳中一些最稀有的金属，如铑，钯，铱和铂。如果要开发真正可持续的化学工艺，继续使用这些元素是一个必须解决的重大挑战。为了解决这个问题，目前的策略利用贱金属（BM）和主族（MG）元素的使用，尽管基于它们单独使用的催化应用分别受到单电子氧化还原事件和它们的氧化还原活性知之甚少的偏好的阻碍。该提案将合并配位化学，有机金属合成和催化领域，旨在揭示融合两种策略最有前途的特性的平台。为了促进和控制BM中心的双电子事件，将使用低价的13族元素来促进合作键活化过程。这将使我们能够为贱金属注入高贵，模仿传统上由贵金属进行的有机转化，并提供超越它们的反应性。该项目将把地球上最丰富的金属Al与可持续和高度丰富的BM配对。BM与低价Al配体结合的催化使用仍然是一个未知的领域，也是建立新化学空间的绝佳机会。INNOBA的发展必将带来独特的可持续催化平台，并最终大幅减少目前由珍贵的NM催化剂催化的无数有机转化的碳足迹。