GENERAL CLINICAL RESEARCH CENTER

全科临床研究中心

• 批准号: 2282145
• 负责人: LAURENCE J MARTON
• 金额: $ 180.16万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-09-30 至 1994-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2282145
• 关键词: clinical trials; human subject

This request by the University of Wisconsin Medical School is for an additional five-year period beginning December 1, 1989 through November 30, 1994 in support of the General Clinical Research Center now in its 4th year of operation. Requested support is as a Discrete Center and is for an adolescent-adult geographic inpatient-outpatient center of (days/visits/year): Inpatient: As-1413, Bs-320 (6 beds at 79% occupancy); outpatient: As-2368, Bs-529; and pediatric age scatter bed inpatient-outpatient support of (days/visits/year): inpatient: As-144, Bs-709; Outpatient: As-56, Bs-237. Requested for AIDS-related research are (days/visits/year): Inpatient: As-176; Outpatient: As-461. In this application 31 peer-reviewed and supported faculty principal investigators and 44 highly qualified faculty co-investigators representing 21 University of Wisconsin Departments have contributed 46 multidisciplinary clinical research protocols. The University of Wisconsin has a long tradition of basic and clinical interdisciplinary research, and its medical school and University of Wisconsin Hospital and Clinics offer an excellent environment for imaginative clinical investigations. The research protocols submitted represent peer-reviewed basic and clinical science investigator initiatives in topics of current and significant medical importance. Areas of focused study in addition to AIDS, include pulmonary problems in premature infants, and children with cystic fibrosis; nutritional effects of minerals in young individuals, and patients with amyotrophic lateral sclerosis; immunology of biological response modifiers; immunologic factors in asthma and marrow transplant; disorders of sleep in adults; ophthalmologic studies of rod sensitivity, and glaucoma; metabolic disorders of diabetes, fat metabolism, lactic acidosis, salt, mood and depression, and human milk; physiologic effects of hyperthermia and immunologic and other agents; pharmacokinetic parameters of cytotoxic agents in patients with cancer; physiologic effects of nursing procedures; and psychosocial roles exhibited by parents under stress. Major emphases on educational opportunities for medical students, houseofficers, post-doctoral fellows, and allied health trainees in clinical research are stressed. The long term objective of this GCRC is to make significant contributions to new knowledge in biomedical science through organized interdisciplinary research activities of faculty basic science and clinical investigators at the University of Wisconsin.

威斯康星大学医学院的这一请求是为了 从 1989 年 12 月 1 日到 11 月的额外五年期 1994 年 12 月 30 日，支持现在的普通临床研究中心 运营第四年。 请求的支持是作为一个离散中心，针对青少年-成人 地理住院-门诊中心（天/次/年）： 住院患者： As-1413、Bs-320（6张床位，入住率79%）；门诊：As-2368、Bs-529； 和儿科年龄分散床住院门诊支持 （天/次/年）：住院患者：As-144、Bs-709；门诊：As-56， Bs-237。 请求进行艾滋病相关研究的时间为（天/次/年）： 住院病人：As-176；门诊：As-461。 在本申请中 31 同行评审和支持的教师主要研究者和 44 名高度 代表 21 所大学的合格教职人员共同研究员 威斯康星州各部门贡献了 46 个多学科临床 研究协议。 威斯康星大学有着悠久的传统 基础和临床跨学科研究及其医学院和 威斯康星大学医院和诊所提供优质的服务 富有想象力的临床研究环境。 研究 提交的方案代表经过同行评审的基础和临床科学 研究者针对当前和重要医学主题的倡议 重要性。 除艾滋病之外的重点研究领域还包括 早产儿和囊肿儿童的肺部问题 纤维化；矿物质对年轻人的营养影响，以及 肌萎缩侧索硬化症患者；生物免疫学 反应调节剂；哮喘和骨髓移植中的免疫因素； 成人睡眠障碍；视杆细胞敏感性的眼科研究， 和青光眼；糖尿病代谢紊乱、脂肪代谢、乳酸 酸中毒、盐、情绪和抑郁以及母乳；生理效应 热疗和免疫及其他药物；药代动力学 癌症患者的细胞毒药物参数；生理 护理程序的影响；以及所表现出的社会心理作用 父母承受压力。 主要强调教育机会 医学生、宿舍管理人员、博士后研究员和专职医疗人员 临床研究的实习生压力很大。 的长期目标 该 GCRC 将为以下领域的新知识做出重大贡献： 通过有组织的跨学科研究进行生物医学科学 基础科学和临床研究人员的活动 威斯康星大学。