CORE--SHARED LABORATORY CORE

该核心支持所有六个实验室共同开展的活动 这是最有效和最经济的单一执行方式 要求高质量控制的操作。核心还支持 维护核心业务中使用的设备以及共同 六个实验室的调查人员共同使用的设备。我们有 确定了通常在 每个单独的实验室，使用类似的程序并要求质量 控制力。将这些整合到单个操作中，使每个 运营效率更高，因此更经济，此外，它还 提供通用标准，并为 不同实验室的技术人员。服务和运营 由核心提供的将包括：准备大型池的一般 使用的单抗，无论是从腹水还是从肿块中获得的 由使用哺乳动物细胞培养系统的培养产生的(内电子技术 Acusyst-R)，制备和测试用于流动的荧光探针 肿瘤和肿瘤的细胞分析、移植和维持 细胞系，保持转基因和SCID的育种记录 老鼠，准备介质，洗碗。一项经验丰富的研究 技术人员将负责核心的日常运营 并将监督初级实验室助手，由其负责 用来洗碗和做更多的日常工作。

This core supports activities common to all six laboratories which are most efficiently and economically conducted as single operations that require high quality control. The core also supports maintenance of equipment used in the core operations as well as common equipment jointly used by investigators in the six laboratories. We have identified those operations which would ordinarily be done separately in each separate laboratory, using similar procedures and requiring quality control. Consolidation of these into single operations makes each operation more efficient and therefore economical, and in addition, it provides a common standard and saves valuable time and effort for the technical staff of the separate laboratories. Services and operations provided by the core will include: preparation of large pools of commonly used monoclonal antibodies whether obtained from ascitic fluid or mass produced from culture using a mammalian cell culture system (Endotronics Acusyst-R), preparing and testing fluorescent probes used for flow cytometric analyses, transplantation and maintenance of tumors and tumor cell lines, maintenance of breeding records for transgenic and SCID mice,.preparation of media, and dishwashing. An experienced research technician will be responsible for the day to day operations of the core and will supervise the junior laboratory helper who will be responsible for dishwashing and for the more routine tasks.