CONTINUOUS POSITIVE AIRWAY PRESSURE EFFECTS IN OBSTRUCTIVE SLEEP APNEA PATIENTS

持续气道正压对阻塞性睡眠呼吸暂停患者的影响

• 批准号: 3785360
• 负责人: FRED INGRAM
• 金额: --
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3785360
• 关键词: clinical trials; human subject; human therapy evaluation; positive pressure breathing; respiratory airway pressure; respiratory therapy; sleep apnea

Evidence from both clinical and research experience indicates that patients with sleep apnea suffer from affective distress as well as decreased efficiency in their daytime functioning. Obstructive sleep apnea (OSA) is fully reversible with continuous positive airway pressure (CPAP). This investigation is to determine which daytime sequelae of OSA are reversible with treatment. The basic design is a 2x4 mixed factorial (using Group and Time), with subjects randomly assigned to either condition in a double-blind fashion.

来自临床和研究经验的证据表明， 患有睡眠呼吸暂停的患者遭受情感困扰， 降低了他们白天的工作效率。阻塞性睡眠 呼吸暂停（OSA）是完全可逆的持续气道正压通气 （CPAP）。这项调查是为了确定哪些日间后遗症的阻塞性睡眠呼吸暂停综合征 通过治疗是可逆的基本设计是2x4混合阶乘 （使用组和时间），受试者随机分配至 以双盲的方式。