NASAL CPAP EFFECTS IN OSA PATIENTS--ARE DAYTIME SEQUELAE REVERSIBLE?

OSA 患者经鼻持续气道正压通气 (CPAP) 的影响——白天的后遗症可以逆转吗？

• 批准号: 5219006
• 负责人: FRED INGRAM
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5219006
• 关键词: clinical research; functional ability; human subject; human therapy evaluation; mood disorders; quality of life; respiratory therapy; sleep apnea; wakefulness

Evidence from both clinical and research experience indicates that patients with sleep apnea suffer from affective distress as well as decreased efficiency in their daytime functioning. Obstructive sleep apnea (OSA) is fully reversible with continuous positive airway pressure (CPAP). This investigation is to determine which daytime sequelae of OSA are reversible with treatment. The basic design is a 2x4 mixed factorial (using Group and Time), with subjects randomly assigned to either condition in a double-blind fashion.

来自临床和研究经验的证据表明 睡眠呼吸暂停患者既有情感困扰，也有 它们白天活动的效率降低。阻塞性睡眠 呼吸暂停(OSA)在持续正压下是完全可逆的 (CPAP)。这项调查是为了确定阻塞性睡眠呼吸暂停综合征的白天后遗症 经治疗后是可逆的。基本设计为2x4混合阶乘 (使用组和时间)，将主题随机分配给 在双盲的情况下。