AUTONOMIC RESPONSE TO PASSIVE UPRIGHT TILT IN MITRAL VALVE PROLAPSE

二尖瓣脱垂被动直立倾斜的自主反应

• 批准号: 3783562
• 负责人: STEPHEN F SCHAAL
• 金额: --
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3783562
• 关键词: autonomic reflex; blood volume; hemodynamics; human subject; hypotension; mitral valve insufficiency; posture

The aims of this study are to (1) identify parasympathetic and sympathetic responses to passive upright tilt in symptomatic patients with mitral valve prolapse; (2) to further characterize the differences in abnormal autonomic responses associated with hypotension; and (3) to examine the effect of volume loading on the autonomic and hemodynamic changes noted with upright tilt.

本研究的目的是(1)识别副交感神经和 有症状患者对被动直立倾斜的交感神经反应 二尖瓣脱垂；(2)进一步描述两者的差异 与低血压相关的异常自主神经反应；以及(3) 检查容量负荷对自主神经和血流动力学的影响 以直立倾斜的方式注意到的变化。