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HUMANITARIAN TREATMENT OF SEVERE PAGET'S DISEASE WITH APD

HUMANITARIAN TREATMENT OF SEVERE PAGET'S DISEASE WITH APD
APD 对严重佩吉特病的人道主义治疗
批准号：
3788170
负责人：
BETTY SAMS ROOF
金额：
$0.0万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3788170
关键词：
Paget's disease of breast diphosphonate human subject human therapy evaluation intravenous administration pharmacokinetics skeletal disorder chemotherapy

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中文摘要
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英文摘要
Paget's Disease of bone can be crippling in deformities, pain and nerve entrapment. Bisphosphonates offer some degree of control of active osteolysis and thereby osteogenesis. They are poorly absorbed from the gastrointestinal tract. IV therapy has maintained responses for 6 months or longer. Thirty mg. infusions of APD (Palmidronate disodium) will be given intravenously for four hours on three successive days.
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HOMEOSTATIC CONTROL OF MINERALS AND HORMONES IN METABOLIC BONE DISEASE
CONTROL OF CA, P, AND MG IN METABOLIC BONE DISEASE
HUMANITARIAN TREATMENT OF SEVERE PAGET'S DISEASE WITH APD
STIMULATION AND INHIBITION OF CALCITONIN BY CANCERS
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