EFFECT OF ETOMOXIR ON GLUCOSE AND LIPID METABOLISM IN DIABETICS

依托莫克西对糖尿病患者葡萄糖和脂质代谢的影响

• 批准号: 3788334
• 负责人: RALPH A DEFRONZO
• 金额: --
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3788334
• 关键词: blood glucose; diabetes mellitus; diabetes mellitus therapy; drug screening /evaluation; enzyme inhibitors; glucose metabolism; human subject; human therapy evaluation; hypoglycemic agents; lipid metabolism

The purpose of this study is to examine the effect of Etomoxir on glucose and lipid metabolism in diabetic subjects. Etomoxir inhibits the enzyme carnitine palmityl transferase I and has been shown to be effective in lowering glucose levels in diabetic animals.

本研究的目的是检查依托莫克西（Etomoxir）对血糖的影响 和糖尿病受试者的脂质代谢。 依托莫克西抑制酶 肉毒碱棕榈酰转移酶 I 已被证明有效 降低糖尿病动物的血糖水平。