COMMUNITY CLINICAL ONCOLOGY PROGRAM-NSABP RESEARCH BASE

这项建议的主要目的是继续发挥 国家外科辅助乳腺和肠道项目（NSABP）已经作为一个 美国国家癌症研究所指定的社区临床肿瘤学项目研究基地 （CCOP）。 具体而言，NSABP将： 临床治疗方案和癌症控制研究方案， 参与CCOP的医生;提供支持服务和教育 为与CCOP有关的工作人员提供培训方案;通过持续的培训方案监测CCOP的业绩。 质量保证计划;继续成功整合CCOP 调查人员对NSABP的整体运作进行了调查。 自1983年以来，作为CCOP的研究基地，NSABP拥有更多的CCOP成员 比其他任何临床合作组都多 由于其 在合作中，NSABP占所有CCOP的约20% 临床试验治疗累积，约15%的受试者 在过去的三年里参与了癌症控制研究。 内 NSABP、CCOP目前占所有辅助研究累积的30%。 通过保持CCOP医生在NSABP中的这种扩大参与， 研究：1）参与临床试验的益处将继续， 在社区环境中更广泛地提供，其中超过80%的 癌症患者接受治疗; 2）回答所提出的治疗问题 研究中的协议将更快地提供;和3）更广泛的部分 将可用于研究和衡量进步 在癌症控制方面。

The primary aim of this proposal is to continue the active role that the National Surgical Adjuvant Breast and Bowel Project (NSABP) has had as an NCI-designated research base for the Community Clinical Oncology Project (CCOP). Specifically, the NSABP will: provide breast and colorectal clinical treatment protocols and cancer control research protocols for participating CCOP physicians; provide support services and educational programs for CCOP-related staff; monitor CCOP performance through ongoing quality assurance programs; continue the successful integration of CCOP investigators into the overall functioning of the NSABP. As a CCOP research base since 1983, the NSABP has more CCOP affiliations than any other clinical cooperative group. As a result of their collaboration, the NSABP has accounted for approximately 20% of all CCOP clinical trial treatment accrual and approximately 15% of all subjects entered on cancer control studies over the past three years. Within the NSABP, CCOPs are currently contributing 30% of all adjuvant study accrual. By maintaining this expanded involvement of CCOP physicians in NSABP studies: 1) the benefits of clinical trial participation will continue to be more widely available in the community setting, where over 80% of all cancer patients are treated; 2) answers to the therapeutic questions posed in study protocols will be available more quickly; and 3) a wider segment of the community will be available for research and measurement of advances in cancer control.