ADVANCES IN THE SYNTHESIS OF OLIGONUCLEOTIDES VIA THE PHOSPHORAMIDITE APPROACH

通过亚磷酰胺方法合成寡核苷酸的进展

• 批准号: 3804713
• 负责人: S L BEAUCAGE
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3804713
• 关键词: amides; nucleic acid chemical synthesis; oligonucleotides; technology /technique

The P.I. has invested considerable effort in writing two long-awaited comprehensive reviews about the synthesis of oligonucleotides by the phosphoramidite approach. The two reviews have been accepted for publication as Tetrahedron Reports. The first review, which comprises more than 500 references concerning the recent advances in oligonucleotide synthesis per se, will be sent for publication by the end of June 1991. The second review covers the application of various phosphoramidite approach. The book chapter (ca. 15-20 pages) is due by September 10, 1991.

私家侦探投入了相当大的努力，写了两个期待已久的 综述了近年来国内外寡核苷酸合成的研究进展， 亚磷酰胺方法。 这两项审查已被接受， 出版物：Tetrahedron Reports 第一次审查包括更多的 参考文献500余篇，涉及寡核苷酸的最新进展 综合报告本身将于1991年6月底送交出版。 第二篇综述了各种亚磷酰胺的应用 approach. 本书的第一章（CA。15-20页）截止日期为1991年9月10日。