Decidual-trophoblast interactions critical for optimal pregnancy outcomes

蜕膜-滋养层相互作用对于最佳妊娠结局至关重要

• 批准号: nhmrc : 1027100
• 负责人: Dr Ellen Menkhorst
• 金额: $ 40.87万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/decidual-trophoblast-interactions-pregnancy-outcomes/110538
• 关键词: Decidual; trophoblast; interactions; critical; optimal

This proposal seeks to identify the critical maternal and embryonic placental factors that regulate the formation of a healthy placenta and thus a healthy pregnancy and baby. Currently there is no way of identifying whether the placenta is forming adequately. The proposed studies are a necessary first step in identifying therapeutic targets for diseases associated with a poorly formed placenta, such as preeclampsia.

该提案旨在确定调节健康胎盘形成的关键母体和胚胎胎盘因素，从而获得健康的妊娠和婴儿。目前还没有办法确定胎盘是否充分形成。拟议的研究是确定与不良胎盘相关疾病（如先兆子痫）治疗靶点的必要的第一步。