CENTER FOR REPRODUCTIVE BIOLOGY RESEARCH

本提案的总体目标是继续支持 范德比尔特大学现有一个跨部门， 多学科生殖生物学研究中心。 的 中心的持续支持将保持效率， 范德比尔特的许多与人口有关的项目正在进行， 将允许在目前没有代表的新区域进行开发。 该中心的研究目标包括调查 男性生殖生理学（精子产生，精子 生物化学，精子代谢，精子成熟，精子 获能、发育男性避孕，以及 男性性行为的神经内分泌控制）， 生殖生理学（受精和着床），以及 生殖内分泌学（生殖激素机制） 行动）。 请求为一个行政核心单位提供支助， 七个核心设施（组织学/显微镜、电子 显微镜检查，组织培养，蛋白磷酸化/循环 核苷酸、激素测定、有机化学/前列腺素， 蛋白质化学）。

The overall objective of this proposal is to continue the support at Vanderbilt University of an existing interdepartmental, multidisciplinary Reproductive Biology Research Center. The continuous support of the Center will maintain the efficiency of many population related projects now active at Vanderbilt and will permit development in a new area not presently represented. The research objectives of the Center include investigations on male reproductive physiology (sperm production, sperm biochemistry, sperm metabolism, sperm maturation, sperm capacitation, development male contraception, and neuroendocrine control of male sexual behavior), on female reproductive physiology (fertilization and implantation), and on reproductive endocrinology (reproductive hormones mechanism of action). Support is requested for an administrative core unit and seven core facilities (Histology/Photomicroscopy, Electron Microscopy, Tissue Culture, Protein Phosphorylation/Cyclic Nucleotide, Hormone Assay, Organic Chemistry/Prostaglandin, and Protein Chemistry).