INVESTIGATIONS OF MASS SPECTRAL TECHNIQUES AND PROCESSES

质谱技术和过程的研究

• 批准号: 3843282
• 负责人: H M FALES
• 金额: --
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3843282
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; mass spectrometry; peptide structure; protein structure

Good Spectra of peptides and proteins have been obtained on JEOL SX-102 spectrometer using a combination of electrospray, FAB, and regular scanning methods. However problems exist in terms of sensitivity, mass range and ease of use. The ion trap mass spectrometer exhibits extremely good sensitivity and has the promise of very high resolution and mass range but the spectra are not simple.

在JEOL SX-102上获得了肽和蛋白质的良好光谱 使用电喷雾，晶圆厂和常规的组合光谱仪 扫描方法。 然而，在敏感性，质量方面存在问题 范围和易用性。 离子陷阱质谱仪表现极高 良好的灵敏度，并有很高的分辨率和质量的希望 范围但光谱并不简单。