SPECIAL PROJECT ON RESEARCH EXCELLENCE--PROSTATE CANCER

前列腺癌中的MSKCC孢子代表了一种创新和 对这种疾病采取全面的方法。我们已经开发出一种 多学科、多机构的临床与检验专业 研究的重点是开发更好的诊断、治疗策略 和预防前列腺癌(CAP)。MSKCC项目的主要优势 包括我们对疾病所有阶段的患者的接触和跟踪 多模式治疗记录(外科、放射肿瘤学和内科 肿瘤学)治疗CAP。此外，我们还设计了一种新的 资源，前列腺癌检测中心，以识别患者在 这种疾病的风险很高。有了这些患者资源，我们可以评估 化学预防战略、独特和创新的方法以改善 检测和分级，并制定更有效的战略 临床局部以及转移性疾病的治疗。 孢子有7个项目，涉及(I)治疗反应的预测因素 (二)单抗特性(三)遗传流行病学(四) 生活质量干预(V)发育性细胞因子免疫疗法(Vi) 生长因子机制和(Vii)化学预防模型。这些项目 由4个核心支持：行政、临床、生物统计和 病理学。此外，我们还创建了发展机制 研究计划和职业发展，并选择了一些项目 以及这些领域的候选人。 我们认为前列腺癌中的MSKCC孢子是一个专注于 将新的生物信息转化为临床和 与其他孢子的合作也将对 治疗和预防前列腺癌的新方法。

The MSKCC SPORE in Prostate Cancer represents an innovative and comprehensive approach to the disease. We have developed a multidisciplinary and multiinstitutional program of clinical and laboratory research focused on the development of better strategies to diagnose, treat and prevent prostate cancer (CaP). Major strengths of the program at MSKCC include our access to patients at all stages of the disease and a track record of multimodal approaches (surgery, radiation oncology and medical oncology) in the treatment of CaP. In addition, we have designed a new resource, the Prostate Cancer Detection Center, to identify patients at high risk for the disease. With these patient resources we can evaluate chemopreventive strategies, unique and innovative approaches to improved detection and staging, and developing more effective strategies for the treatment of clinically localized, as well as, metastatic disease. The SPORE has 7 projects that address (i) predictors of response to therapy (ii) monoclonal antibody characterization (iii) genetic epidemiology (iv) quality of life interventions (v) developmental cytokine immunotherapy (vi) growth factor mechanisms and (vii) chemoprevention models. These projects are supported by 4 Cores: Administrative, Clinical, Biostatistics and Pathology. In addition, we have created the mechanism for Developmental Research Programs and Career Development and have selected some projects and candidates in these areas. We believe that the MSKCC SPORE in Prostate Cancer is a program focused on the translation of new biological information into the clinic and in collaboration with other SPORE's as well positioned to make an impact on new approaches to cure and prevent prostate cancer.