老年男性性类固醇对促性腺激素分泌的调节-猫眼课题宝

老年男性性类固醇对促性腺激素分泌的调节

批准号：

3849073

负责人：

RANDALL J URBAN

金额：

$0.0万

依托单位：

UNIVERSITY OF TEXAS MED BR GALVESTON

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

未结题

起止时间：

至

来源：

https://reporter.nih.gov/project-details/3849073

关键词：

aging blood chemistry gonadotropin releasing factor gonadotropins hormone regulation /control mechanism human subject hypothalamic pituitary axis intravenous administration male secretion sex hormones steroid hormone metabolism steroid hormone receptor

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英文摘要

The hypothesis was that hypothalamic-pituitary secretion of gonadotropins in response to sex-steroids is altered in aging men. Healthy older men and young men were studied by infusing sex-steroids and blocking their endogenous receptors. Multiple-parameter deconvolution analysis was used to delineate secretion and clearance parameters of gonadotropins measured through frequent blood samples.

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