Defining the Physiology and Therapeutic Potential of Inhibin

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Shutdown of ovarian function at menopause depletes the female body of circulating oestrogen and inhibins. Whilst it is known that oestrogen deprivation is bad for bone health, little is known about the impact of inhibin loss. I have made a mouse that lacks functional inhibins, so that we can understand the body wide consequences of inhibin loss at menopause. Additionally, I have found a way to mass produce inhibins, allowing us to explore the potential of inhibin replacement therapies.