Defining role of inflammatory signals in enhancing motoneuron regeneration

点击翻译按钮获取中文摘要

Spinal cord injury is a devastating event that has a life-long impact on the patient’s life with wide-reaching social and economic effects. In this proposal we examine how inflammatory signals boost neuronal regeneration after injury. Furthermore, we define how new neurons are able to integrate into existing spinal circuitry. Out work provides critical insight and hold keys to unlocking strategies for future restorative therapies in the brain or spinal cord.