CORD BLOOD DIAGNOSIS OF COAGULOPATHIES IN HIGH-RISK NEWBORNS

高危新生儿凝血病的脐带血诊断

• 批准号: 3884250
• 负责人: THOMAS ABSHIRE
• 金额: --
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3884250
• 关键词: blood coagulation tests; blood disorder diagnosis; diagnosis design /evaluation; disseminated intravascular coagulation; fibrin; fibrinogen; human pregnant subject; human subject; newborn human (0-6 weeks); plasmin; pregnancy circulation; thrombin

Coagulopathies occur frequently in the sick newborn but are difficult to diagnose because of insensitivities in our current screening tests. This study will measure specific fibrinogen/fibrin fragments to develop a more specific and sensitive test of disseminated intravascular coagulation (DIC) and to discern the role of Thrombin act. or plas. in high risk newborns.

凝固性疾病经常发生在患病的新生儿中，但 很难诊断，因为我们目前的情况不敏感 筛查测试。这项研究将测量具体的 纤维蛋白原/纤维蛋白片段发展为更具特异性和 弥散性血管内凝血(DIC)和 来辨别凝血酶的作用。或者是Plas。处于高风险中 新生儿。